St. Luke’s Hospital is a JCAHO accredited hospital providing primary and acute healthcare services to Polk County, North Carolina and the upstate of South Carolina. We offer a variety of healthcare services in a beautiful setting at the foot of the Blue Ridge Mountains.
Located near the intersection of Interstate 26 and Route 108 in Columbus, North Carolina, St. Luke’s Hospital is 40 miles southeast of Asheville, North Carolina and 25 miles northwest of Spartanburg, South Carolina.

St. Luke’s is the only hospital in its primary service area and it provides a 24-hour physician staffed emergency department and specialized medical and surgical services usually associated with much larger hospitals. Also residing on the St. Luke’s campus is the Polk County EMS and Hospice of the Carolina Foothills.

St. Luke’s Hospital enjoys close affiliations with Spartanburg Regional Medical Center and Mission-St. Joseph’s Health System, both major tertiary care centers, only a few minutes away by helicopter or ambulance.